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Entitled Gratitude, the 51 sculptures have been created by a number of artists and are accompanied by real-life audio stories, recorded by famous voices, about key workers.
The free exhibition opens in Birmingham next month.
It is then due to move on to Manchester, Edinburgh and London.
The sculptures will be auctioned off at a later date, with "substantial proceeds" going to NHS Charities Together.
They have been designed by artists and designers including Pam Hogg, Andrew Logan, Kitty Joseph, Kate Malone and the project's creative ambassador, Dame Zandra Rhodes.
Artist Mr A Singh said his sculpture, entitled Community Strength, was dedicated to voluntary key workers from diverse backgrounds.